Stem Cell Therapy

Regenerative Medicine

Regenerative Medicine for Pain Management and Wellness

Regenerative medicine is a cutting-edge form of treatment that involves biological therapies to assist in your body’s natural healing process. At Innovative Pain and Wellness, we utilize your body’ s platelets and plasma, or a liquid allograft derived from the amniotic components of donated placenta, to advance soft tissue repair, replacement, and reconstruction. Injecting these powerful components has been shown to stimulate healing and speed repair for bone, muscle, joint, soft tissue and nerve injuries through a process called cell signaling (please refer to our website for supportive literature). Our therapies are can be used to treat a wide range of acute and chronic injuries and pain.  Patients who have a recent injury as well as patients who have failed conservative conventional treatments such as anti­ inflammatory medications, injections therapy, physical therapy or chiropractic, surgery, and rest may benefit from treatment.

Ask your Innovative Pain and Wellness provider about a consultation to explore individualized treatment plans for each patient and determine if you are a candidate for regenerative procedures.

There are a number of conditions that can be treated with regenerative medicine at Innovative Pain and Wellness including but not limited to:

  • Arthritis of the joints and Spine
  • Pain in joints and muscle
  • Muscle Strains
  • Ligament tears or sprains
  • Various forms of tendinitis or tendinosis (chronic tendonitis) or tendon injury
  • Plantar Fasciitis
  • Meniscus Tears
  • Soft tissue Injury
  • Compression nerve injuries (carpal tunnel, ulnar, radial, and peroneal neuropathy)

Schedule a consultation today!

Using Your Own Cells with Platelet-Rich Fibrin Matrix

Platelet-rich fibrin matrix (PRFM) is a concentrated form of the platelets and plasma in your blood, obtained by processing your blood in a special centrifuge. When an injury occurs, platelets naturally begin the healing process in your body. The platelets release cell signaling proteins that attract your own body’s inherent stem cells to the injured area. By injecting concentrated PRFM into an area of concern, your body recognizes this site as a priority, working to heal more quickly and thoroughly.  As part of our multimodal treatment algorithms at Innovative Pain and Wellness, we engage you in a physical therapy regimen to advance the healing process.

Using Donated Cells with Liquid Amnion

Liquid amnion is liquid allograft derived from the amniotic components of donated placenta, to advance soft tissue repair, replacement, and reconstruction. The donor of the donated human tissue has been deemed free from risk factors for and clinical evidence of infection due to relevant communicable diseases and other exclusionary disease conditions through the review of the donor’s medical records, including medical/behavior risk assessment and a recent physical examination.  Similar to PRFM, by injecting liquid amnion into an area of concern, your body recognizes this site as a priority, working to heal more quickly and thoroughly.  As part of our multimodal treatment algorithms at Innovative Pain and Wellness, we engage you in a physical therapy regimen to advance the healing process.

Amniotic Stem Cell Treatment

Amniotic regenerative medicine treatment is an injectable, flowable tissue graft derived from human placental amnion which functions as a biologic structural matrix to facilitate and enhance tissue healing and repair.

  • Amniotic regenerative medicines are a natural biologic alternative to synthetic products.
  • Amniotic regenerative medicines are derived from live, healthy, prescreened donors after live child birth.
  • Donor selection and amniotic tissue recovery and processing procedures meet or exceed all applicable medical industry standards.
  • Reduces fibroblast infiltration and promotes tissue reconstruction by down-regulating TGF-B receptor expression by fibroblasts.
  • Contains important growth factors and proteins, which promote collagen matrix formation and cellular proliferation while minimizing the formation of scar tissue.
  • Composed of collagens and structural proteins that support angiogenesis, tissue growth, and collagen production during tissue regeneration and repair.

Bone Marrow Aspirate

Stem cells are a blank slate that can transform into any type of cell in the human body through a process called differentiation.

Stem cell therapy is the process of introducing these cells into areas of the body where damage has occurred, such as a sports injury or arthritic knees, where they help regenerate the entire area.

Bone Marrow Aspirate is the process of harvesting your regenerative medicines from the rich sources found in the iliac crest of your pelvis.

During the procedure your physician will remove a sample of your regenerative medicines and concentrate them for injection into an injured area of your body. The high concentration of regenerative medicines works directly at the site of injury to increase the healing potential.

Call today to schedule a consultation!

Frequently Asked Questions

Will my insurance pay for treatments?

Your initial consultation will typically be covered by your insurance. However, many insurance companies do not cover the cost of the actual procedures, as they are currently considered investigational. The overall cost of treatment will depend on the type of treatment recommended and whether one or multiple treatment rounds are necessary.

How will I know if I need more treatments?

Patients may require one to three treatments and typically experience improvement in pain and mobility within 4-6 weeks with continued improvement over 3 months after procedure. Our goal is to have an 80-90% improvement in pain and function.

How long before I can resume activity?

This is an outpatient procedure that results in little down time for the patient. Typically, we do suggest patients rest after the procedure, but they can return to normal activities within about three days.

Why don’t I get “stem cells”?

Regenerative medicine is an exciting and evolving form of healing.  The more research that is done on this therapy, the more scientists push towards using the bodies own, natural healing.  The term “stem cells” has become a synonym in society for regenerative medicine when, in fact, very rarely are actual stem cells indicated or used.  In fact, the FDA is working towards a ban of the use and marketing the words “stem cells” as it is misleading.  PRFM is the frontline treatment of choice for most conditions.  It uses the bodies own natural healing properties and the outcomes are proving superior to older products commonly referred to in the public as “stem cells”.  At Innovative Pain and Wellness, we strive to provide a fully transparent and ethical patient experience.  Therefore, we have chosen to follow the current guidelines and not use the words “stem cells.”

What conditions can be treated?

There are a number of conditions that can be treated with regenerative medicine at Innovative Pain and Wellness including, but not limited to:

  • Arthritis of the joints and Spine
  • Pain in joints and muscle
  • Muscle Strains
  • Ligament tears or sprains
  • Various forms of tendinitis or tendinosis (chronic tendonitis) or tendon injury
  • Plantar Fasciitis
  • Meniscus Tears
  • Soft tissue Injury
  • Compression nerve injuries: carpal tunnel, ulnar, radial, and peroneal neuropathy.

How do you determine the proper treatment for an injury?

The decision, made by your Innovative Pain and Wellness physician, is individualized and based on personal experience as well as the published research of other practitioners who perform similar procedures around the world. Depending on the severity of the injury, and/or disease, some patients require several treatments.

How is PRFM delivered to the injured area?

Your own blood will be drawn by a professional about 10 minutes prior to your injection.  The blood is then placed in a special centrifuge specifically designed to separate the platelets and plasma for seven minutes.  The platelets and plasma are then mixed with a unique fibrin matrix for injection.  While the blood is spinning, your Innovative Pain and Wellness physician will accommodate you into the procedure room and prepare you for the simple injection.  Once you are ready, the physician will use ultrasound guidance or X-Ray for targeted placement of your body’s platelet rich fibrin matrix into the damaged tissue.

Will the injections be painful?

A varying degree of discomfort is also associated with the initial injection anesthetic at the injured site.  We offer IV sedation for all procedures, and your provider will discuss this with you.  With or without sedation, we may use a local anesthetic numbing agent.  Usually the anesthetic last for a couple of hours. You many experience slight discomfort for the first 24 to 72 hours during the healing process.  Tylenol can also be used if you have no contraindications (please see guidelines below).

How long before I can resume activity?

This is an outpatient procedure that results in little down time for the patient. Typically, we do suggest you rest the day of the procedure, but you can usually return to normal activities the next day.

How will I know if I need more treatments?

Patients may require one to three treatments and typically experience improvement in pain and mobility within 4-6 weeks with continued improvement over 3 months after procedure. Our goal is to have an 80-90% improvement in pain and function. This can vary depending on the severity of your disease and the intensity of your activity level during the healing process.

Are there any adverse effects to the treatments?

The most common side effect is post-traumatic discomfort. For the first 72 hours, some patients may experience low grade fevers, swelling at the site of the injection, mild body aches and fatigue. These symptoms are rare.  Specific risks and benefits for each treatment of interest will be discussed at the time of the initial consultation.

How do I get started?

Schedule an initial consultation at Innovative Pain and Wellness and bring all documentation related to your pain including any imaging studies previously obtained. During your consultation we will review your medical history and do an extensive exam, as well as review any films.  An Innovative Pain and Wellness physician will then create a multimodal treatment plan and discuss the plan with you.

Is this therapy expensive?

Your initial consultation will typically be covered by your insurance. Your Innovative Pain and Wellness provider will briefly discuss the potential cost based on your insurance situation. The overall cost for the treatment will ultimately depend on the type of treatment recommended and whether one or multiple treatment rounds are necessary. We offer extremely competitive pricing for regenerative therapy, and use insurance benefits anytime possible. In general, the treatment cost is roughly comparable to typical injection co-pays.

It is likely that your insurance benefits will cover the physical therapy after the treatments.                                       

Journal Articles and Research on Regenerative Medicine

Stem Cell Therapy

Concentrated Bone Marrow Aspirate for the Treatment of Chondral Injuries and Osteoarthritis of the Knee A Systematic Review of Outcomes – Read Full Article – ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE

Clinical Outcome of Bone Marrow Concentrate in Knee Osteoarthritis – Read Full Article – JOURNAL of PROLOTHERAPY

Emerging Applications of Stem Cell and Regenerative Medicine to Sports Injuries – Read Full Article – JOURNAL for ORTHOPAEDIC SPORTS MEDICINE

Percutaneous Injection of Autologous Bone Marrow Concentrate Cells Significantly Reduces Lumbar Discogenic Pain Through 12 Months – Read Full Article – STEM CELLS

Autologous Bone Marrow Concentrate: Review and Application of a Novel Intra-Articular Orthobiologic for Cartilage Disease – Read Full Article – THE PHYSICIAN AND SPORTS MEDICINE

Clinical outcome of autologous bone marrow aspirates concentrate (BMAC) injection in degenerative arthritis of the knee – Read Full Article – EUROPEAN JOURNAL OF ORTHOPAEDIC SURGERY & TRAUMATOLOGY

Injection of Bone Marrow Concentrate for Refractory Tennis Elbow – Read Full Article – SAUDI JOURNAL OF SPORTS MEDICINE

Increased Knee Cartilage Volume in Degenerative Joint Disease using Percutaneously Implanted, Autologous Mesenchymal Stem Cells – Read Full Article – PAIN PHYSICIAN

Percutaneous Autologous Bone Marrow Injection in the Treatment of Distal Meta-diaphyseal Tibial Nonunions and Delayed Unions – Read Full Article – JOURNAL OF ORTHOPAEDIC TRAUMA

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